Screening and characterization of stable Pin1-knockdown esophageal squamous cell carcinoma cell strains
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چکیده
منابع مشابه
Role of Brg1 in progression of esophageal squamous cell carcinoma
Objective(s): Epigenetic regulation of gene expression can be carried out through chromatin remodeling enzymes such as SWI/SNF. Brg1 also known as SMARCA4 is a catalytic subunit of SWI/SNF, which is necessary for MMPs expression. Matrix metalloproteinases (MMPs) are known as important player enzymes during tumor progression and metastasis. Aberrant epigenetic modification of chromatin should be...
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Esophageal cancer (EC) is the eighth common cancer and the sixth most common cause of death from cancer worldwide. Esophageal squamous cell carcinoma (ESCC) remains the most common type of EC in the developing world and an important health problem in high-risk areas. Most of ESCC cases present in late stages, resulting in delayed diagnosis and poor prognosis. Prevention is the most effective st...
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esophageal cancer (ec) is the eighth most common cancer and sixth most frequent cause of cancer mortality worldwide. esophageal squamous cell carcinoma (escc) is the most common type of ec. escc develops by progression from premalignant lesions, which are called esophageal squamous dysplasia (esd). prevention is the most effective strategy for controlling this disease. generally, two methods ma...
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Telomerase activation is one of the main pathways to immortalize cancer cells. In many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. Esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural ha...
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Objective(s): CD44 is a member of the cell adhesion molecules family. Naturally, CD44S, along with CD44V3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. The purpose of this research is to evaluate the CD44S and CD44V3 expression in Esophageal Squamous Cell Carcinoma (ESCC) and to reveal their correlations wit...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2010
ISSN: 2219-2859
DOI: 10.11569/wcjd.v18.i14.1485